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Disclaimer:

This material is intended for scientific and educational purposes for licensed healthcare professionals only. The content summarizes findings from independently conducted and published research studies, as cited. Results reflect the specific study populations, designs, and settings described in each publication and should not be generalized beyond those parameters. These findings do not constitute a claim of efficacy or performance beyond the approved indications of the device as authorized by the K-FDA(식약처). Clinical outcomes may vary depending on the patient, operator experience, and clinical setting.

Clinical Evidence on EVIS X1

Discover the latest bibliography on EVIS X1. The EVIS X1 endoscopy system introduces a range of technologies that aim to support the way physicians can detect, characterize and treat gastrointestinal disorders. This page serves as a resource for researchers, clinicians, and healthcare professionals interested in staying informed about the impact of EVIS X1 in endoscopic procedures. Each entry includes a link to further reading.

TXI (Texture and Color Enhancement Imaging)

The incoming image is split and the texture and brightness are enhanced before the separate images are merged back together. Additional color enhancements are made to more clearly define subtle tissue differences.1

 

TXI technology is not intended to replace histopathological sampling as a means of diagnosis.

 

 

[References]

1) Sato, Tomoya, TXI: Texture and Color Enhancement Imaging for Endoscopic Image Enhancement, Journal of Healthcare Engineering, 2021, 5518948, 11 pages, 2021. 

TXI in Esophagogastroduodenoscopy

Barrett's esophagus

Title (Link to abstract)

Comparison of Texture and Color Enhancement Imaging with White Light Imaging in 52 Patients with Short-Segment Barrett’s Esophagus – PubMed (nih.gov)

Author

Ikeda A, et al

Publication Year

2023

Journal

Medical Science Monitor

Endoscopes

GIF-H290Z

 

Title (Link to abstract)

Texture and Colour Enhancement Imaging (TXI) versus White Light Endoscopy for Detection of Dysplasia Within Barrett’s Esophagus: a Pilot Study

Author

Young E, et al.

Publication Year

2025

Journal

Digestion

Endoscopes

GIF-HQ190 and GIF-EZ1500

 

EGC

Title (Link to abstract)

Usefulness of texture and color enhancement imaging (TXI) in early gastric cancer found after Helicobacter pylori eradication – PubMed (nih.gov)

Author

Shijimaya T, et al

Publication Year

2023

Journal

Scientific Reports

Endoscopes

GIF-H290Z

 

Title (Link to abstract)

Usefulness of third-generation narrow band imaging and texture and color enhancement imaging in improving visibility of superficial early gastric cancer: A study using color difference – PubMed (nih.gov)

Author

Kawasaki A, et al

Publication Year

2022

Journal

DEN Open

Endoscopes

GIF-EZ1500, GIF-XZ1200, or GIF-H290Z

 

Title (Link to abstract)

Efficacy of Texture and Color Enhancement Imaging in visualizing gastric mucosal atrophy and gastric neoplasms – PubMed (nih.gov)

Author

Ishikawa T, et al

Publication Year

2021

Journal

Scientific Reports

Endoscopes

GIF-EZ1500,GIF-H290Z

Gastritis

Title (Link to abstract)

Endoscopic diagnosis of Helicobacter pylori gastritis using white light imaging and texture and color enhancement imaging – PubMed (nih.gov)

Author

Kitagawa Y, et al

Publication Year

2023

Journal

Endoscopy International Open

Endoscopes

GIF-H290Z

 

ESD

Title (Link to abstract)

Endoscopic submucosal dissection and tunneling procedures using novel image-enhanced technique – ScienceDirect

Author

Zaheer N, et al.

Publication Year

2022

Journal

VideoGIE

Endoscopes

GIF-HQ190

 

TXI in Colonoscopy

Neoplasia detection

Title (Link to abstract)

Assessing the effectiveness of texture and color enhancement imaging versus white-light endoscopy in detecting gastrointestinal lesions: A systematic review and meta-analysis

Author

Shahzil M, et al

Publication Year

2025

Journal

DEN Open

Endoscopes

Not applicable

 

Title (Link to abstract)

Texture and color enhancement imaging versus high definition white-light endoscopy for detection of colorectal neoplasia: a randomized trial – PubMed (nih.gov)

Author

Antonelli G, et al.

Publication Year

2023

Journal

Endoscopy

Endoscopes

EVIS X1

 

Title (Link to abstract)

Texture and Color Enhancement Imaging Improves Colonic Adenoma Detection: A Multicenter Randomized Controlled Trial – PubMed (nih.gov)

Author

Young E, et al.

Publication Year

2023

Journal

Gastroenterology

Endoscopes

CF-HQ190

 

Title (Link to abstract)

Detection of colorectal adenomas with texture and color enhancement imaging: Multicenter observational study – PubMed (nih.gov)

Author

Sakamoto T, et al.

Publication Year

2022

Journal

Digestive Endoscopy

Endoscopes

CF-H290ECI, CF-HQ290I, CF-HQ290ZI, PCF-H290TI, PCF-H290ZI, or GIF-H290T

Note

This study was supported by funding from Olympus.

 

Title (Link to abstract)

Comparison of Image-Enhanced Endoscopy Techniques for Colorectal Lesion Detection and Characterization: A Network Meta-Analysis of Randomized Controlled Trials

Author

Li Y, et al

Publication Year

2025

Journal

The American Journal of Gastroenterology

Endoscopes

Not applicable

 

Title (Link to abstract)

Assessing the effectiveness of texture and color enhancement imaging versus white-light endoscopy in detecting gastrointestinal lesions: A systematic review and meta-analysis

Author

Shahzil M, et al

Publication Year

2025

Journal

DEN Open

Endoscopes

Not applicable

 

Title (Link to abstract)

The efficacy of texture and color enhancement imaging (TXI) observation in the detection of colorectal lesions: a multicenter, randomized controlled trial (deTXIon study)

Author

Toyoshima N et al.

Publication Year

2025

Journal

Endoscopy

Endoscopes

CF-EZ1500DI

Note

This study was supported by funding from Olympus.

 

Title (Link to abstract)

Efficacy of Texture and Color Enhancement Imaging for Identification of Colorectal Polyps: A Prospective Crossover Randomized Trial

Author

Biwata Y, et al.

Publication Year

2025

Journal

Digestive Endoscopy

Endoscopes

CF- HQ290ZI or PCF- H290ZI

UC

Title (Link to abstract)

Usefulness of texture and color enhancement imaging in assessing mucosal healing in patients with ulcerative colitis – PubMed (nih.gov)

Author

Hayashi Y, et al

Publication Year

2022

Journal

Gastrointestinal Endoscopy

Endoscopes

PCF-H290ZI

 

Title (Link to abstract)

Usefulness of Novel Image-Enhanced Endoscopy for Predicting Maintenance of Clinical Remission in Ulcerative Colitis

Author

Mamiya Y et al.

Publication Year

2025

Journal

Digestive Diseases and Sciences

Endoscopes

PCF-H290ZI , CF-HQ290

 

ESD

Title (Link to abstract)

Pristine submucosal visibility using Texture and Color Enhancement Imaging during saline-immersion rectal endoscopic submucosal dissection

Author

Lemmers A, et al

Publication Year

2022

Journal

Endoscopy

Endoscopes

GIF-HQ190

 

TXI in Pancreatobiliary

ERCP

Title (Link to abstract)

The usefulness of texture and color enhancement imaging to identify the minor papilla orifice

Author

Goda Y, et al.

Publication Year

2024

Journal

DEN Open

Endoscopes

TJF-Q290V

 

Title (Link to abstract)

Distinguishing the papilla of Vater during biliary cannulation using texture and color enhancement imaging: A pilot study

Author

Miyaguchi K, et al.

Publication Year

2022

Journal

DEN Open

Endoscopes

TJF-Q290V

 

Title (Link to abstract)

Visibility of the biliary orifice after precut papillotomy: Comparison between white light imaging and texture and color enhancement imaging

Author

Toyonaga H, et al.

Publication Year

2024

Journal

Journal of Hepato-biliary -Pancreatic Sciences

Endoscopes

TJF-Q290V

 

Title (Link to abstract)

Efficacy of texture and color enhancement imaging for short-type single-balloon enteroscopy-assisted biliary cannulation in patients with Roux-en-Y gastrectomy: Multicenter study (with video)

Author

Tanisaka Y, et al.

Publication Year

2024

Journal

DEN

Endoscopes

SIF-H290S

POCS

Title (Link to abstract)

New image-enhanced cholangioscopy for the diagnosis of cholangiocarcinoma

Author

Ishii T, et al.

Publication Year

2023

Journal

Endoscopy

Endoscopes

CHF-B290

 

Title (Link to abstract)

Usefulness of texture and color enhancement imaging in peroral cholangioscopy

Author

Tanisaka Y, et al.

Publication Year

2023

Journal

Endoscopy

Endoscopes

CHF-B290

* The information on this page was last updated on April, 2026.