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Esophageal Case 3

Prof. Stefan Seewald​

GastroZentrum Hirslanden, Zurich

Disclaimer:

  • NBI™ and TXI™ Technologies are not intended to replace histopathological sampling as a means of diagnosis​
  • NBI™ and TXI™ Technologies are 510(k) cleared in the United State. This case study is being furnished to provide example of NBI and TXI technology use. The GIF-EZ1500 used in this case is not available in the US market at this time, nor is there an established time for it’s release. The safety and effectiveness of this product and/or the use of these products has not yet been established in the United States market.​
  • The positions and statements made herein by Prof. Seewald are based on Prof. Seewald’s experiences, thoughts and opinions. As with any product, results may vary, and the techniques, instruments, and settings can vary from facility to facility. The content hereof should not be considered as a substitute for carefully reading all applicable labeling, including the Instructions for Use. Please thoroughly review the relevant user manual(s) for instructions, risks, warnings, and cautions. Techniques, instruments, and setting can vary from facility to facility. It is the clinician’s decision and responsibility in each clinical situation to decide which products, modes, medications, applications, and settings to use.​
  • The EVIS X1™ endoscopy system is not designed for cardiac applications. Other combinations of equipment may cause ventricular fibrillation or seriously affect the cardiac function of the patient. Improper use of endoscopes may result in patient injury, infection, bleeding, and/or perforation. Complete indications, contraindications, warnings, and cautions are available in the Instructions for Use (IFU)
Procedure Information


Scope:GIF-EZ1500

Case: Squamous Cell Carcinoma

Organ: Esophagus

Patient information: M, 74

Medical history: Smoker

1. WLI

#WLI #A7 structure enhancement #Auto Iris

A suspicious reddish lesion can be identified at 6 to 9 o’clock.

2. TXI™ technology

#TXI technology Mode 1 #A7 structure enhancement #Auto Iris

TXI™ technology suggests a larger area that may be interpreted as reflux esophagitis at the first glance.

3. NBI™ technology

#NBI technology Mode 1 #A7 structure enhancement #Auto Iris

However, with NBI technology abnormal intrapapillary capillary loops (IPCLs) can be identified which require closer examination.

4. Near Focus with NBI™ technology

#NBI technology #NBI technology Color Mode 1 #B7 Structure Enhancement #Auto Iris

Abnormal IPCLs can be confirmed under near focus, suggesting a squamous cell carcinoma.

5. Lugol staining (WLI)

#WLI + Lugol Staining #A7 structure enhancement #Auto Iris

To confirm the extend of the carcinoma, Lugol staining was applied. Various Lugol-voiding lesions can be identified.

6. Lugol Staining (TXI™ technology)

#TXI™ technology 1 + Lugol Staining #A7 structure enhancement #Auto Iris

Under TXI™ technology mode 1, the delineation is supported by stronger color contrast of the carcinoma. The pink color sign is more prominent compared to white light.

Case video

Overall Comment

This case presents an incidentally detected squamous cell carcinoma, NBI technology was helpful for detection and characterization in this case. TXI technology in combination with Lugol was helpful to delineate the lesion.

* Specifications, design and accessories are subject to change without any notice or obligation on the part of the manufacturer.

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