Duodenum Case 9
Prof. Dr. Fatih Aslan
Koc University Hospital
Istanbul, Turkey
Disclaimer:
- NBI™ and TXI™ Technologies are not intended to replace histopathological sampling as a means of diagnosis
- The positions and statements made herein by Prof. Dr. Fatih Aslan are based on Prof. Dr. Fatih Aslan’s experiences, thoughts and opinions. As with any product, results may vary, and the techniques, instruments, and settings can vary from facility to facility. The content hereof should not be considered as a substitute for carefully reading all applicable labeling, including the Instructions for Use. Please thoroughly review the relevant user manual(s) for instructions, risks, warnings, and cautions. Techniques, instruments, and setting can vary from facility to facility. It is the clinician’s decision and responsibility in each clinical situation to decide which products, modes, medications, applications, and settings to use.
- The EVIS X1™ endoscopy system is not designed for cardiac applications. Other combinations of equipment may cause ventricular fibrillation or seriously affect the cardiac function of the patient. Improper use of endoscopes may result in patient injury, infection, bleeding, and/or perforation. Complete indications, contraindications, warnings, and cautions are available in the Instructions for Use (IFU)
- NBI™, RDI™, and TXI™ technologies are 510(k) cleared in the United States. This case study is being furnished to provide examples of NBI™, RDI™, and TXI™ technology use. The GIF-EZ1200 used in this case is not available in the US market at this time, nor is there an established time for its release. The safety and effectiveness of this product and/or the use of these products has not yet been established in the United States market
Scope: GIF-XZ1200, GIF-EZ1500
Case: Duodenal second part tubular adenoma with high grade dysplasia
Organ: Duodenum Second Part
3. NBI™ technology + magnification
#NBI #A8 structure enhancement #optic magnification
4. NBI™ technology + magnification
#NBI #A8 structure enhancement #optic magnification
5. NBI™ technology + magnification
#NBI #A8 structure enhancement #optic magnification
Case Video
Pre-procedural assessment of the lesion was performed using the GIF-XZ1200 endoscope. Thanks to its manual optical magnification capability, the entire surface of the lesion was thoroughly examined, aided by the magnifying effect of water immersion. Subsequently, a standard Olympus straight hood was attached to the GIF-EZ1500 endoscope, and the ESD procedure was carried out using the water pressure method with a DualKnife™ device (2.0 mm Knife Length). During the procedure, the contrast enhancement provided by TXI™ technology mode was found to be particularly useful for distinguishing the submucosa from the muscularis propria. In addition, the EDOF™ (Extended Depth of Field) technology function of the scope was frequently utilized, enabling close and effective dissection throughout the procedure. These visual advantages are believed to contribute not only to procedural efficiency but also to the prevention of potential adverse events. To minimize the risk of delayed complications such as perforation or bleeding, the resection site was securely closed using absorbable barbed sutures.
Overall Comment
This case highlights the evaluation of an adenoma located in the second portion of the duodenum using various endoscopic imaging modalities, the ability to perform detailed anatomical distinction, and the safe closure of the post-resection defect using a minimally invasive suturing technique following advanced endoscopic resection. Imaging technologies such as TXI™ and NBI™ technology enabled clear visualization of lesion margins and vascular patterns. During the ESD procedure, the enhanced contrast provided by TXI™ technology allowed for clear distinction between the submucosa and muscularis propria layers. After resection, the defect was successfully closed using barbed sutures, thereby reducing the risk of complications. This case demonstrates how novel imaging modes facilitate precise preoperative assessment of duodenal lesions. Furthermore, it underscores how advances in endoscopic technology and instrumentation enable the minimally invasive treatment of premalignant lesions while also allowing for the effective prevention of potential adverse events.
* Specifications, design and accessories are subject to change without any notice or obligation on the part of the manufacturer.
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