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Pancreatobiliary case 1

Jong Ho Moon, MD, PhD, FASGE, FACG, FJGES

Professor of Medicine

Director, Digestive Disease Center

SoonChunHyang University School of Medicine,

Bucheon/Seoul, Korea

Il Sang Shin, MD, PhD

Assistant Professor

Digestive Disease Center

SoonChunHyang University School of Medicine,

Bucheon/Seoul, Korea

Procedure Information


Scope: TJF-Q290V 

Case Findings: Suspicious ampullary mass on computed tomography (CT) scan

Organ: Ampulla of Vater

Patient information: 72-year-old, Female

Medical history: No past medical history 

1. WLI Observation

Classic appearance of ampulla of Vater without distinctive features

Enhancement : A7
NBI Mode : NA
TXI Mode : NA
RDI Mode : NA
BAI-MC : On

2. NBI Observation

Precise delineation of boundaries between covering fold and papillary orifice

Enhancement : A7
NBI Mode : 2
TXI Mode : NA
RDI Mode : NA
BAI-MC : On

3. TXI Observation

More clear observation of anatomical structures such as papillary orifice, frenulum, and circular fold

Enhancement : A7
NBI Mode : NA
TXI Mode : 2
RDI Mode : NA
BAI-MC : On

4. RDI Observation

Easier identification of the hemostatic condition and possible bleeding point of ampullary orifice after endoscopic forceps biopsy

Enhancement : A7
NBI Mode : NA
TXI Mode : NA
RDI Mode : 1
BAI-MC : On

Case Video

This video shows the usefulness of a new image enhanced endoscopy system in identifying a regular papilla in a patient with suspected ampullary mass on computed tomography (CT) scan. Under white-light imaging (WLI), regular papilla with classic appearance was observed. Under narrow-band imaging (NBI), covering folds and papillary orifices were more apparent. TXI mode 2 shed more light on the anatomical features of the surface than NBI, while maintaining visual naturalness and being less disturbed from bile acids similar to WLI. After forceps biopsy, RDI mode 1 more easily identified the hemostatic condition of ampulla of Vater, making it easier to determine whether there is a bleeding point that requires endoscopic hemostasis. Even if the papilla appears normal, the application of TXI and RDI modes can help to accurately assess the anatomical structure and abnormality of the ampulla of the Vater.

Overall Comment

This case demonstrates that observation using TXI and RDI modes in ampulla of Vater, although which seems to be normal, can be helpful for an effective observation and safe biopsy sampling by keeping the biopsy location with pancreatic duct as far as possible. With less disturbance from bile acid than narrow-band imaging, TXI emphasizes the difference in color tone of the mucosal surface, enhancing the accurate evaluation of the anatomical structure including frenulum, circular fold, and even polypoid nodule of papillary orifice. RDI can effectively identify hemostatic status and possible bleeding points, helping to quickly determine whether endoscopic hemostasis is necessary after tissue sampling.

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