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Author: Dr.David Fielding
Royal Brisbane & Women’s Hospital
Procedure Information


Scope: BF-H1100

Location: Tracheal mucosa

Patient information: Male, 73 years old

Medical history: Past history head and neck cancer. Presentend with rapid deterioration with mediastinal adenopathy

1. WLI
(small indistinct nodule on trachea pars membranacea)

An unusual position for a nodule and possible to be overlooked by a bronchoscopist looking further down the airway.

2. TXI
(trachea and pars membranacea)

TXI shows the nodule more clearly and quickly shows it is more than just a nonspecific collection of mucus which would be the usual reason for this appearance. Furyther the right lateral lower tracheal wall can now be shown to have similar nodules, and a diffuse mucosal nodular process is now suspected.

3. NBI
(mucosal nodule in pars membranacea)

Complex dilated vessels coursing over and through the lesion highly suggestive of invasive malignancy

4. TXI
(left main bronchus)

The suspicion of a disseminated endobronchial process seen in the trachea is now confirmed in the left main bronchus with multiple well defined nodules

5. TXI
(left main bronchus)

TXI provides a distinct edge to the nodules, quickly demonstrating to the bronchoscopist that the nodules are pathologic. In this case it is obvious with many nodules. But sometimes if there is only one or two nodules they could be mistaken for secretions in this location, except for the way TXI shows distinct edges.

6. NBI
(left main bronchus)

Complex dilated vessels coursing through some nodules in foregraound of pars membranacea, consistent with malignancy

Case video

In white light view there is a suspicion of mucosal abnormality, but often in this location there are mucus secretions, which could be bypasssed by the bronchoscopist. However changing to TXI gives a view of the index mucosal nodular lesion being a distinct pathologic process, seen in the foreground.
It does this in a way which is relatively close to white light in terms of general appearance with there being no need to adjust to a different way of viewing. Additionally with TXI it is quickly apparent that there are multiple other nodules on the far wall. NBI also shows the vascular changes of these nodules and also shows the multiple nature of the nodules.

Overall Comment

Even though there was other evidence of metastatic disease ( mediastinal adenopathy) defining the extent of the endobronchial mucosal involvement with malignant nodularity gave a clear emphasis on the rapidly progressing nature of this metastatic involvement. TXI helped the clinician to rapidly observe the true extent of the nodules, which in this location could have been easily overlooked as just non-specific secretions. NBI helped to then confirm the suspicion of malignancy.

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