Angelo Naselli, MD. Prof. Paolo Puppo, MD. Oncological Urology, Istituto Clinico Humanitas Mater Domini, Castellanza, Varese, Italy
Disclaimer:
- NBI™ Technology is not intended to replace histopathological sampling as a means of diagnosis.
- The positions and statements made herein by Dr. Naselli and Dr. Puppo are based on their collective experiences, thoughts and opinions. As with any product, results may vary, and the techniques, instruments, and settings can vary from facility to facility. The content hereof should not be considered as a substitute for carefully reading all applicable labeling, including the Instructions for Use. Please thoroughly review the relevant user manual(s) for instructions, risks, warnings, and cautions. Techniques, instruments, and setting can vary from facility to facility. It is the clinician’s decision and responsibility in each clinical situation to decide which products, modes, medications, applications, and settings to use.
- Dr. Naselli and Dr. Puppo are compensated consultants of the Olympus Corporation.
- All images are courtesy of Dr. Naselli and Dr. Puppo, except where otherwise noted.
Relapse Bladder Cancer, age 73, male
Comments
A flat tumor evidenced by NBI™ Technology which was seen as a scar in WLI. Histology showed pTa, High grade.
Relapse Bladder Cancer, age 71, male
Comments
A low grade recurrence which was missed in WLI after BCG topic therapy. Histology showed pTa, Low grade.
Relapse Bladder Cancer, age 48, male
Comments
A high grade recurrence which was missed in WLI (no adjuvant instillation). Histology showed pTa, High grade.
Relapse Bladder Cancer, age 73, male
Comments
A recurrence which was missed in WLI. Histology showed pTa, Low grade.
Relapse Bladder Cancer, age 64, male
Comments
A high grade recurrence which was missed in WLI after BCG topic therapy. Histology showed pTa, High grade.
Flat Lesion, age 53, female
Comments
Patient with positive urine cytology and negative standard WLI cystoscopy (history of high grade non-invasive bladder cancer). The red areas evidenced by NBI™ Technology were then biopsied and CIS was found. Histology showed CIS.
Papillary peduncular Tumor, age 67, male
Comments
An area of micro-papillary tumor was completely missed by WLI, but was enhanced with NBI™ Technology, with the vascular cores of the papillary structure showing a characteristic “speckled appearance. Histology showed pTa, Low grade.
Papillary sessile tumor, age 80, female
Comments
Micro Papillary Flat Tumor. An area of tumor was shown as a “red patch” by WLI but was enhanced with NBI™ Technology in patient submitted to BCG topic therapy. Histology showed pTa, High grade.
Papillary sessile tumor, age 57, male
Comments
Early papillary tumor. A recurrence which was overlooked under WLI inspection and was enhanced by NBI™ Technology. Histology showed pTa, Low grade.
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