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Angelo Naselli, MD. Prof. Paolo Puppo, MD. Oncological Urology, Istituto Clinico Humanitas Mater Domini, Castellanza, Varese, Italy

Relapse Bladder Cancer age 73, male

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NBI

Comments

A flat tumor evidenced by NBI which was seen as a scar in WLI. Histology showed pTa, High grade.

Relapse Bladder Cancer age 71, male

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NBI

Comments

A low grade recurrence which was missed in WLI after BCG topic therapy. Histology showed pTa, Low grade.

Relapse Bladder Cancer age 48, male

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NBI

Comments

A high grade recurrence which was missed in WLI (no adjuvant instillation). Histology showed pTa, High grade.

Relapse Bladder Cancer age 73, male

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NBI

Comments

A recurrence which was missed in WLI. Histology showed pTa, Low grade.

Relapse Bladder Cancer age 64, male

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NBI

Comments

A high grade recurrence which was missed in WLI after BCG topic therapy. Histology showed pTa, High grade.

Flat Lesion age 53, female

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NBI

Comments

Patient with positive urine cytology and negative standard WLI cystoscopy (history of high grade non invasive bladder cancer). The red areas evidenced by NBI were then biopsied and CIS was found. Histology showed CIS.

Papillary peduncular Tumor age 67, male

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NBI

Comments

An area of micro-papillary tumor was completely missed by WLI, but was enhanced with NBI, with the vascular cores of the papillary structure showing a characteristic “speckled appearance. Histology showed pTa, Low grade.

Papillary sessile tumor age 80, female

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NBI

Comments

Micro Papillary Flat Tumor. An area of tumor was shown as a “red patch” by WLI but was enhanced with NBI in patient submitted to BCG topic therapy. Histology showed pTa, High grade.

Papillary sessile tumor age 57, male

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NBI

Comments

Early papillary tumor. A recurrence which was overlooked under WLI inspection and was enhanced by NBI.
Histology showed pTa, Low grade.

Images and comments by Angelo Naselli, MD. Prof. Paolo Puppo, MD.

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