Author: Daisuke Himeji, MD, PhD
Miyazaki Prefectural Miyazaki Hospital, Japan
Endoscopy Center, Department of Internal Medicine, Department of Medical Informatics
Patient information: Female in her 70s
She consulted a local doctor after suffering from exertional dyspnea and wheezing that had continued for 3 months. A chest CT showed a mass compressing the airway in the left S6. Bronchoscopy was performed and squamous cell carcinoma was diagnosed. The patient was referred to us for surgery, and we performed bronchoscopy to assess the feasibility of surgery.
6. Close-up image of the left lower lobe lung cancer (NBI)
The abnormal vessels on the tumor surface and beneath it can be observed clearly with Narrow Band Imaging (NBI).
In comparison with conventional white light imaging, the TXI mode noticeably enhances the properties and distribution of vessels on the surface of the tumor, as well as the characteristics of the longitudinal wall, thereby providing images that facilitate assessment of the degree of infiltration of the tumor into the bronchial wall.
Squamous cell lung cancer (resected specimen findings)
Tumor cells of various sizes are proliferating in a honeycomb or sheet-like pattern. Necrosis occurs in some cells. The tumor cells have a short spindle-shape and large polygonal cytoplasm, as well as polygonal nuclei. The tumor has infiltrated into the bronchial cartridge and lymph nodes.
We performed a bronchoscopy to examine the feasibility of resection. While the image quality of white light images was extremely clear, using the TXI mode enhanced the vascular properties, highlighting the network of vessels on the tumor surface and the thickening of the longitudinal wall, thereby facilitating comprehension of the characteristics of the lesion and the extent of infiltration. It was finally determined that resection would be feasible. We subsequently performed left lower lobe sleeve resection and mediastinal lymph node dissection. The cytological examination of the resected bronchial stump was negative.
Department of Internal Medicine, Miyazaki Prefectural Miyazaki Hospital
Dr. Gen-ichi Tanaka, Dr. Ryoichi Matsumoto, Dr. Ritsuya Shiiba
Department of Surgery, Miyazaki Prefectural Miyazaki Hospital
Dr. Kiichiro Beppu, Dr. Seiichi Odate
Department of Anatomic Pathology, Miyazaki Prefectural Miyazaki Hospital
Dr. Kousuke Marutsuka, Dr. Murasaki Aman
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