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Case : Snare resection of tumor in the proper segment of the left upper lobe

Li Shiyue Professor Guidance Expert

The First Affiliated Hospital of Guangzhou Medical University

 

 

Tang Chunli Professor Operation Expert

The First Affiliated Hospital of Guangzhou Medical University

Procedure information


Scope: BF-Q290

Location: Left upper lobe

Patient information: Male, 18 years old

Medical history: Intermittent coughing for two years, hemoptysis for one week, no fever, chest pain, or dyspnea. Chest CT indicates a neoplasm in the left upper lobe.

1. Left upper lobe (WLI)

A neoplasm was seen blocking the lumen of the left upper lobe

2. Left upper lobe (TXI)

The neoplasm in the proper segment of the left upper lobe was clearly seen in TXI mode with rich blood vessels on the surface of the tumor

3. Left upper lobe (RDI)

The tumor in the proper segment of the left upper lobe shows no deep blood vessels under RDI mode

4. After snare resection of the tumor in the proper segment of the left upper lobe (WLI)

Obvious bleeding occurred after snare resection of the tumor in the proper segment of the left upper lobe, and the lens was easily blurred

5. After snare resection of the tumor in the proper segment of the left upper lobe (RDI)

The bleeding site was seen in the RDI mode obviously after snare resection of the tumor in the proper segment of the left upper lobe, as indicated by the arrow

Case Video

The bleeding site can be clearly displayed in RDI mode

Hemostasis of active bleeding

Pathological diagnosis

  • Two pieces of gray-white tissues (1.2cm×0.8cm×0.5cm and 1.5cm×1.0cm×0.5cm in size) in the proper segment of the upper lobe of left lung was seen with the naked eye (full covered)
  • Endoscopic findings: The tumor cells in the tissues (of the proper segment of the upper lobe of left lung) examined were composed of nonkeratinized squamous cells with the shape of sheet and polygon, intermediate cells, and mucus-secreting columnar cells. Most of the intermediate cells had round or oval nuclei with nucleoli, and a small number were columnar cells that secrete mucus, forming small glands, tubules or cysts. Nuclear division was not obvious and no necrosis was observed.
  • Molecular pathology results: MAML2(+)
  • Immunohistochemistry results: TTF1(-), NapsinA(-), P40(partially+), SMARCA4(+), ALK-P(D5F3)(-), ALK-P(Neg)(-), Ki67(hot-spot 15%+),PD-L1(E1L3N)(-),PD-L1(Neg)(-),CK5/6(+),CK7(+)
  • Special staining results: Mucicarmine (+)
  • Pathological diagnosis: Tissue (of the proper segment of the upper lobe of left lung) changes in line with bronchial low-grade mucinous epidermoid carcinoma

Overall Comment

Compared with the WLI mode of the bronchoscope, the TXI mode can display deeper vascular structures, which help determine the treatment of lesions. If bleeding occurs during treatment or biopsy, the RDI mode can help avoid the impact of blood on the bronchoscope camera. Especially for beginners, it can reduce the effect of blood contamination on the camera’s field of view, and help them easily see the bleeding site and accurately implement local hemostasis at the same time.

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